Free radicals, largely produced as byproducts of energy metabolism, can damage tissue and speed up the aging process through a process called oxidative stress. Managing a healthy level of free radicals is achieved by antioxidants, which can be obtained through diet and are produced naturally by the body. The GPX1 gene produces a protein (enzyme) that protects the body from the damaging effects of free radicals. GPX1 is often called the body's "master antioxidant."
However, a significant portion of the population have a dysfunctional version of GPX1 and are at increased risk of oxidative stress.
How Does the GPX-1 Gene Work?
GPX1 is a "selenoprotein" which means to function properly the GPX1 protein requires selenium. Due to the importance of GPX1 in maintaining a healthy level of free radicals, achieving an adequate level of daily selenium is essential. Here's how the process works in about 67% of people: