Rootine is built on 10+ years of nutrigenetic science, technology, and algorithm / AI development.
The genetic variants we analyze must reach medical-grade bar-of-proof to impact nutrient requirements humans.
More than 400 peer-reviewed studies back our method and we've brought medical-grade testing to you - at a fraction of the cost.
Rootine is built on 10+ years of nutrigenetic science, technology, and algorithm development.
The genetic variants we analyze must reach medical-grade bar-of-proof to impact nutrient requirements humans.
More than 400 peer-reviewed studies back our method and we've brought medical-grade testing to you - at a fraction of the cost.
tldr:
18 nutrients research-proven to provide benefit and safety in humans. Nutrients are delivered via slow-release microbeads to optimize absorption.
Nutrigenetics: science of how your genes influence which nutrients you need. In addition, we look at nutrient blood levels and use to hyper-personalize your formula.
Two at-home tests: DNA Test (50+ gene variants) and Vitamin Test (finger prick). Tests are processed in our licensed medical genetics lab.
The nutrient suite consists exclusively of EFSA-described nutrients proven to confer benefit - and be safe - in humans. EFSA is the highest authority on nutrient claims, significantly more strict than the FDA.
More than 3 years of R&D lead to our industry-leading nutrient delivery system: microbeads. This form-factor enables precision dosing to the mcg and the 10+ hour slow-release matrix provides enhanced absorption and maintenance of optimal blood levels.
The nutrient suite consists exclusively of EFSA-described nutrients proven to confer benefit - and be safe - in humans. EFSA is the highest authority on nutrient claims, significantly more strict than the FDA.
More than 3 years of R&D lead to our industry-leading nutrient delivery system: microbeads. This form-factor enables precision dosing to the mcg and the 10+ hour slow-release matrix provides enhanced absorption and maintenance of optimal blood levels.
methylcobalamin
Source: Fermentation
Vitamin B12 helps regulate the homocysteine level in blood, which is influenced by certain genetic variants. High homocysteine levels have a negative impact on heart health and should be kept low.
riboflavin
Source: Fermentation
Vitamin B2 can aid in stabilizing homocysteine levels, but only if a certain genetic variant is present. If this is not the case, vitamin B2 has no effect on homocysteine levels.
selenomethionine
Source: Mineral
Selenium is an important component of many enzymes, some of which can neutralize free radicals. Certain genotypes need higher amounts of selenium to increase antioxidant protection.
methylfolate / folic acid
Source: Synthetic
Folate helps regulate the homocysteine level in blood, which is influenced by certain genetic variants. High homocysteine levels have a negative impact on heart health and should be kept low.
manganese sulphate
Source: Mineral
Manganese is an important component of many enzymes and has an impact free radical protection and joint health. Certain genotypes benefit in these areas if manganese intake is increased.
ascorbic acid
Source: Fermentation
Vitamin C is a strong water-soluble antioxidant and can have a positive impact on cognitive health, eye health, joint health and protection from free radicals.
methylcobalamin
Source: Fermentation
Vitamin B12 helps regulate the homocysteine level in blood, which is influenced by certain genetic variants. High homocysteine levels have a negative impact on heart health and should be kept low.
riboflavin
Source: Fermentation
Vitamin B2 can aid in stabilizing homocysteine levels, but only if a certain genetic variant is present. If this is not the case, vitamin B2 has no effect on homocysteine levels.
selenomethionine
Source: Mineral
Selenium is an important component of many enzymes, some of which can neutralize free radicals. Certain genotypes need higher amounts of selenium to increase antioxidant protection.
methylfolate / folic acid
Source: Synthetic
Folate helps regulate the homocysteine level in blood, which is influenced by certain genetic variants. High homocysteine levels have a negative impact on heart health and should be kept low.
manganese sulphate
Source: Mineral
Manganese is an important component of many enzymes and has an impact free radical protection and joint health. Certain genotypes benefit in these areas if manganese intake is increased.
ascorbic acid
Source: Fermentation
Vitamin C is a strong water-soluble antioxidant and can have a positive impact on cognitive health, eye health, joint health and protection from free radicals.
pyroxidine hydrochloride
Source: Pharmaceutical
Vitamin B6 helps regulate the homocysteine level in blood, which is influenced by certain genetic variants. High homocysteine levels have a negative impact on heart health and should be kept low.
cholecalciferol
Source: Biological
Vitamin D3 can be produced by the skin when exposed to sunlight and is an important factor for healthy bones. Certain genotypes require higher doses of this vitamin to maintain optimal bone health.
ubiquinone
Source: Biological
Coenzyme Q10 is an important antioxidant that the body produces but production tends to decline with age. CoQ10 needs the action of a certain gene to be converted to the active form Ubiquinol.
d-alpha tocopheryl acetate
Source: Bio. / Pharma
Vitamin E is a strong lipid-soluble antioxidant and can have a positive impact on cognitive health, eye health, joint health and protection from free radicals.
alpha lipoic acid
Source: Biological / Syn.
Alpha-lipoic acid (ALA) is a mitochondrial compound involved in energy metabolism. ALA provides a short but potent reduction of oxidation by increasing anti-oxidant enzymes.
methylsulfonylmethane
Source: Pharmaceutical
This organic sulphur compound reduces the aggressiveness of the immune system and can help protect joints in certain genotypes.
pyroxidine hydrochloride
Source: Pharmaceutical
Vitamin B6 helps regulate the homocysteine level in blood, which is influenced by certain genetic variants. High homocysteine levels have a negative impact on heart health and should be kept low.
cholecalciferol
Source: Biological
Vitamin D3 can be produced by the skin when exposed to sunlight and is an important factor for healthy bones. Certain genotypes require higher doses of this vitamin to maintain optimal bone health.
ubiquinone
Source: Biological
Coenzyme Q10 is an important antioxidant that the body produces but production tends to decline with age. CoQ10 needs the action of a certain gene to be converted to the active form Ubiquinol.
dl-alpha tocopheryl acetate
Source: Bio. / Pharma
Vitamin E is a strong lipid-soluble antioxidant and can have a positive impact on cognitive health, eye health, joint health and protection from free radicals.
alpha lipoic acid
Source: Biological / Syn.
Alpha-lipoic acid (ALA) is a mitochondrial compound involved in energy metabolism. ALA provides a short but potent reduction of oxidation by increasing anti-oxidant enzymes.
methylsulfonylmethane
Source: Pharmaceutical
This organic sulphur compound reduces the aggressiveness of the immune system and can help protect joints in certain genotypes.
magnesium citrate
Source: Mineral
Magnesium is an essential component of more than 300 enzymes, and therefore particularly important for metabolism, the functioning of the muscle cells, and also bone health.
zinc bisglycinate
Source: Mineral
Zinc is needed by the body to correctly metabolize macronutrients, properly construct proteins and enzymes, to maintain normal bone, and to create new DNA.
sito-, campe-, signma-
Source: Biological (pine)
In genotypes where omega 3 fatty acids have a negative impact on HDL cholesterol levels, phytosterols are a good alternative to help improve cholesterol levels.
copper sulphate
Source: Mineral
Copper is an important component of many enzymes and is therefore an important trace element for metabolism. It has also been shown to reduce the aggressiveness of the immune system and to improve eye health.
calcium carbonate
Source: Biological
Calcium is an important component of many bodily functions. Certain genotypes require higher amounts of calcium for optimal bone health and to aid in detoxification.
iron bisglycinate
Source: Mineral
Iron is an important component of blood as it allows hemoglobin to carry oxygen. Some genetic variants can cause the excessive absorption of iron, which can damage organs.
magnesium citrate
Source: Mineral
Magnesium is an essential component of more than 300 enzymes, and therefore particularly important for metabolism, the functioning of the muscle cells, and also bone health.
zinc bisglycinate
Source: Mineral
Zinc is needed by the body to correctly metabolize macronutrients, properly construct proteins and enzymes, to maintain normal bone, and to create new DNA.
sito-, campe-, signma-
Source: Biological (pine)
In genotypes where omega 3 fatty acids have a negative impact on HDL cholesterol levels, phytosterols are a good alternative to help improve cholesterol levels.
copper sulphate
Source: Mineral
Copper is an important component of many enzymes and is therefore an important trace element for metabolism. It has also been shown to reduce the aggressiveness of the immune system and to improve eye health.
calcium carbonate
Source: Biological
Calcium is an important component of many bodily functions. Certain genotypes require higher amounts of calcium for optimal bone health and to aid in detoxification.
iron bisglycinate
Source: Mineral
Iron is an important component of blood as it allows hemoglobin to carry oxygen. Some genetic variants can cause the excessive absorption of iron, which can damage organs.
A U-shaped curve describes when too much - or too little - of something has a negative impact. In essence, it describes a nutrient "sweet spot" - which is different for every person. We identify your ideal range and dose for each nutrient and deliver it in a bespoke daily formula.
The science of nutrigenetics powers our method. Nutrigenetics is the science of how slight genetic variations, inherited from your parents, impact how your body absorbs and metabolizes nutrients.
Our DNA Test analyzes 50+ SNPs that are proven to impact nutrient needs due to the influence on nutrient absorption, distribution, metabolism, excretion, and receptor function. All gene variants adhere to our medical-grade bar of proof to impact nutrient needs: 3 different studies by 3 different researchers in 3 different test populations (3x3x3 min.).
Our Blood Test (finger prick) reveals the nutrient level in the body, which helps to determine which nutrients you need more of, less of, or not at all.
Tests are analyzed in our licensed medical-genetics laboratory certified ISO 9001, 15189, and 22000 - boasting 100% genetic testing accuracy over 10 years, determined by an external proficiency program. Your data is private and secure.
Our DNA Test analyzes 50+ SNPs (single nucleotide polymorpisms) that are proven to impact nutrient needs due to the influence on nutrient absorption, distribution, metabolism, excretion, and receptor function. All gene variants adhere to our medical-grade bar of proof to impact nutrient needs: 3 different studies by 3 different researchers in 3 different test populations (3x3x3 min.).
Our Vitamin Test (finger prick to analyze blood levels) reveals the nutrient level in the body, which helps to determine which nutrients you need more of, less of, or not at all.
Tests are analyzed in our licensed medical-genetics laboratory certified ISO 9001, 15189, and 22000 - boasting 100% genetic testing accuracy over 10 years, determined by an external proficiency program. Your data is 100% private and secure.
determine your precise nutrient needs at home
analyze 50+ genes and 4+ blood nutrient levels
accurate dosing of 18 research-backed ingredients
licensed medical genetics lab with 100% data security
slow-release microbeads provide optimal absorption
precision dosing of each nutrient to the mcg or mg
nutrigenetic method backed by 400+ PR studies
10+ years of technology backing precision formulas
100% testing accuracy, 200k+ analyses per month
in-house and 3rd party testing + state-of-the-art QC
algorithm auto-adjusts nutrient formula over time
50+ genes and 4+ blood levels
18 research-backed ingredients
licensed medical genetics lab
slow-release microbeads
precision doses of each nutrient
backed by 400+ PR studies
10+ years of pioneering tech
100% genetic testing accuracy
in-house and 3rd party testing
algorithm auto-adjusts over time
Now, we all have access to affordable medical-grade testing and data-driven solutions to determine our unique biological needs and elegantly meet them. Through technology, Rootine ties biometric testing and nutritional solutions together.
Common variations in your genetic code impact how you absorb, distribute, metabolize, and excrete key vitamins, minerals, and other nutritional substances. These slight variations are called single nucleotide polymorphisms (abbreviated “SNPs”) and alter the way the gene product is built. Slight variations in the corresponding enzymes and receptors adversely impact their function. The Rootine DNA Test analyzes 50+ gene variants that are research proven to impact nutrient needs.
- 11% of people have a SNP in their VDR gene, which creates the Vitamin D Receptor. This variation results in a less efficient binding between vitamin D and the receptor. Carriers need ~2x more vitamin D.
- 85% of people have SNPs in their MTHFR gene, which creates the enzyme that activates folate. These variations reduce the efficiency of this enzyme. Carriers often need pre-activated folate (methylfolate).
- 0.5% of people have SNPs in their HFE gene which alters the way the body regulates iron absorption. Carriers absorb far too much iron which becomes poisonous to their body. All iron is removed from their formula.
We’re proud to exclusively analyze and provide nutrient recommendations based on gene variants that are supported by medical-grade bar-of-proof to influence nutrient needs. This way you know your formula is built on verified science, not conjecture.
- Dr. Daniel Wallerstorfer PhD, Bsc, Founder of Rootine
Blood testing is one of the most effective ways to determine which nutrients you need and helps monitor the success of a supplement program or dietary change over time. Our inexpensive and quick blood testing helps enable frequent re-testing to prove that you're formula is achieving optimal blood nutrient levels - or details how to adjust your formula to account for levels that are lagging or have jumped too high.
Previously, blood testing was expensive, required a visit to your doctor, and took weeks to get results back. With the development of our new rapid blood testing platform, we are bringing inexpensive and efficient blood analaysis to our customers so they can test often and see real, data-driven health improvements.
The frequency of blood testing is a primary indicator or the success of a program. If a patient, client, or customer only tests once a year, there is little data to base programmatic changes on. Rootine's platform allows for frequent testing, which means more data and formula precision, without breaking the bank.
- Dr. Javier Diaz PharmD, FAARM, FMNM, ABAAHP, RPh, METS
Every person has a sweet spot for their optimal daily intake of vital nutrients. The level for each nutrient is determined by a variety of factors, including genetics, current nutrient status, age, weight, health status, diet, lifestyle and more. To add complexity, these ideal intakes can change over time due to increasing age, health changes, and fluctuations in nutrient levels.
In short, determining optimal nutritional intakes is an incredibly complex equation unique to every person. The current standard system of RDAs (recommended daily allowances) and DVs (daily values) for nutrient intakes lacks these critical nuances that directly determine each person’s unique needs. These systems are a well-intentioned approach to provide a succinct reference to the level of nutrients most people need; however, optimal outcomes are built on precision, personalized nutrition - not population-level generalizations. Rootine is built to fill this gap.
The elegance of Rootine's approach is two-fold: 1) by analyzing DNA data, blood status, and relevant lifestyle factors (age, weight, habits, dietary preferences, etc.), we are able to create the most complete and accurate understanding of an individual's true requirements, and 2) our innovative microbead delivery system provides precision dosing of each nutrient to the micogram or milligram - coupled with enhanced delivery from the slow-release and spatial nutrient separation. Microbeads are the leading oral nutrient delivery system.
We saw a hole in the personalized health industry. Comprehensive testing solutions were lacking and no brand had the capability of offering bespoke formulas with precise doses. We created Rootine to fill this gap.
- Rachel Sanders MBA, Founder of Rootine