Extraordinary Science for Extraordinary People

Rootine is built on 10+ years of nutrigenetic science, technology, and algorithm / AI development.

The genetic variants we analyze must reach medical-grade bar-of-proof to impact nutrient requirements humans.

More than 400 peer-reviewed studies back our method and we've brought medical-grade testing to you - at a fraction of the cost.

VEGETARIAN & SUGAR FREE

18 PROVEN NUTRIENTS

10+ HR SLOW RELEASE

PRECISION DOSES

MEDICAL-GRADE LAB

100% SECURE DATA

Extraordinary Science for Extraordinary People

Rootine is built on 10+ years of nutrigenetic science, technology, and algorithm development.

The genetic variants we analyze must reach medical-grade bar-of-proof to impact nutrient requirements humans.

More than 400 peer-reviewed studies back our method and we've brought medical-grade testing to you - at a fraction of the cost.

tldr:

18 nutrients research-proven to provide benefit and safety in humans. Nutrients are delivered via slow-release microbeads to optimize absorption.

Nutrigenetics: science of how your genes influence which nutrients you need. Metabolomics: deep insights into metabolism and nutrient function. Both sciences are used to hyper-personalize your formula.

Two at-home tests: DNA Test (50+ gene variants) and Blood Nutrient Test (80+ metabolites). Tests are processed in our licensed medical genetics lab.

Nutrients & Delivery

The nutrient suite consists exclusively of EFSA-described nutrients proven to confer benefit - and be safe - in humans. EFSA is the highest authority on nutrient claims, significantly more strict than the FDA.

More than 3 years of R&D lead to our industry-leading nutrient delivery system: microbeads. This form-factor enables precision dosing to the mcg and the 10+ hour slow-release matrix provides enhanced absorption and maintenance of optimal blood levels.

Nutrients & Delivery

The nutrient suite consists exclusively of EFSA-described nutrients proven to confer benefit - and be safe - in humans. EFSA is the highest authority on nutrient claims, significantly more strict than the FDA.

More than 3 years of R&D lead to our industry-leading nutrient delivery system: microbeads. This form-factor enables precision dosing to the mcg and the 10+ hour slow-release matrix provides enhanced absorption and maintenance of optimal blood levels.

Vitamin B12

methylcobalamin

Source: Fermentation

learn more

Vitamin B12 helps regulate the homocysteine level in blood, which is influenced by certain genetic variants. High homocysteine levels have a negative impact on heart health and should be kept low.

Supporting studies.

Vitamin B2

riboflavin

Source: Fermentation

learn more

Vitamin B2 can aid in stabilizing homocysteine levels, but only if a certain genetic variant is present. If this is not the case, vitamin B2 has no effect on homocysteine levels.

Supporting studies.

Selenium

selenomethionine

Source: Mineral

learn more

Selenium is an important component of many enzymes, some of which can neutralize free radicals. Certain genotypes need higher amounts of selenium to increase antioxidant protection.

Supporting studies.

Folate (B9)

methylfolate / folic acid

Source: Synthetic

learn more

Folate helps regulate the homocysteine level in blood, which is influenced by certain genetic variants. High homocysteine levels have a negative impact on heart health and should be kept low.

Supporting studies.

Manganese

manganese sulphate

Source: Mineral

learn more

Manganese is an important component of many enzymes and has an impact free radical protection and joint health. Certain genotypes benefit in these areas if manganese intake is increased.

Supporting studies.

Vitamin C

ascorbic acid

Source: Fermentation

learn more

Vitamin C is a strong water-soluble antioxidant and can have a positive impact on cognitive health, eye health, joint health and protection from free radicals.

Supporting studies.

Vitamin B12

methylcobalamin

Source: Fermentation

learn more

Vitamin B12 helps regulate the homocysteine level in blood, which is influenced by certain genetic variants. High homocysteine levels have a negative impact on heart health and should be kept low.

Supporting studies.

Vitamin B2

riboflavin

Source: Fermentation

learn more

Vitamin B2 can aid in stabilizing homocysteine levels, but only if a certain genetic variant is present. If this is not the case, vitamin B2 has no effect on homocysteine levels.

Supporting studies.

Selenium

selenomethionine

Source: Mineral

learn more

Selenium is an important component of many enzymes, some of which can neutralize free radicals. Certain genotypes need higher amounts of selenium to increase antioxidant protection.

Supporting studies.

Folate (B9)

methylfolate / folic acid

Source: Synthetic

learn more

Folate helps regulate the homocysteine level in blood, which is influenced by certain genetic variants. High homocysteine levels have a negative impact on heart health and should be kept low.

Supporting studies.

Manganese

manganese sulphate

Source: Mineral

learn more

Manganese is an important component of many enzymes and has an impact free radical protection and joint health. Certain genotypes benefit in these areas if manganese intake is increased.

Supporting studies.

Vitamin C

ascorbic acid

Source: Fermentation

learn more

Vitamin C is a strong water-soluble antioxidant and can have a positive impact on cognitive health, eye health, joint health and protection from free radicals.

Supporting studies.

Vitamin B6

pyroxidine hydrochloride

Source: Pharmaceutical

learn more

Vitamin B6 helps regulate the homocysteine level in blood, which is influenced by certain genetic variants. High homocysteine levels have a negative impact on heart health and should be kept low.

Supporting studies.

Vitamin D3

cholecalciferol

Source: Biological

learn more

Vitamin D3 can be produced by the skin when exposed to sunlight and is an important factor for healthy bones. Certain genotypes require higher doses of this vitamin to maintain optimal bone health.

Supporting studies.

CoQ10

ubiquinone

Source: Biological

learn more

Coenzyme Q10 is an important antioxidant that the body produces but production tends to decline with age. CoQ10 needs the action of a certain gene to be converted to the active form Ubiquinol.

Supporting studies.

Vitamin E

d-alpha tocopheryl acetate

Source: Bio. / Pharma

learn more

Vitamin E is a strong lipid-soluble antioxidant and can have a positive impact on cognitive health, eye health, joint health and protection from free radicals.

Supporting studies.

ALA

alpha lipoic acid

Source: Biological / Syn.

learn more

Alpha-lipoic acid (ALA) is a mitochondrial compound involved in energy metabolism. ALA provides a short but potent reduction of oxidation by increasing anti-oxidant enzymes.

Supporting studies.

MSM

methylsulfonylmethane

Source: Pharmaceutical

learn more

This organic sulphur compound reduces the aggressiveness of the immune system and can help protect joints in certain genotypes.

Supporting studies.

Vitamin B6

pyroxidine hydrochloride

Source: Pharmaceutical

learn more

Vitamin B6 helps regulate the homocysteine level in blood, which is influenced by certain genetic variants. High homocysteine levels have a negative impact on heart health and should be kept low.

Supporting studies.

Vitamin D3

cholecalciferol

Source: Biological

learn more

Vitamin D3 can be produced by the skin when exposed to sunlight and is an important factor for healthy bones. Certain genotypes require higher doses of this vitamin to maintain optimal bone health.

Supporting studies.

CoQ10

ubiquinone

Source: Biological

learn more

Coenzyme Q10 is an important antioxidant that the body produces but production tends to decline with age. CoQ10 needs the action of a certain gene to be converted to the active form Ubiquinol.

Supporting studies.

Vitamin E

dl-alpha tocopheryl acetate

Source: Bio. / Pharma

learn more

Vitamin E is a strong lipid-soluble antioxidant and can have a positive impact on cognitive health, eye health, joint health and protection from free radicals.

Supporting studies.

ALA

alpha lipoic acid

Source: Biological / Syn.

learn more

Alpha-lipoic acid (ALA) is a mitochondrial compound involved in energy metabolism. ALA provides a short but potent reduction of oxidation by increasing anti-oxidant enzymes.

Supporting studies.

MSM

methylsulfonylmethane

Source: Pharmaceutical

learn more

This organic sulphur compound reduces the aggressiveness of the immune system and can help protect joints in certain genotypes.

Supporting studies.

Magnesium

magnesium hydroxide

Source: Mineral

learn more

Magnesium is an essential component of more than 300 enzymes, and therefore particularly important for metabolism, the functioning of the muscle cells, and also bone health.

Supporting studies.

Zinc

zinc bisglycinate

Source: Mineral

learn more

Zinc is needed by the body to correctly metabolize macronutrients, properly construct proteins and enzymes, to maintain normal bone, and to create new DNA.

Supporting studies.

Phytosterols

sito-, campe-, signma-

Source: Biological (pine)

learn more

In genotypes where omega 3 fatty acids have a negative impact on HDL cholesterol levels, phytosterols are a good alternative to help improve cholesterol levels.

Supporting studies.

Copper

copper sulphate

Source: Mineral

learn more

Copper is an important component of many enzymes and is therefore an important trace element for metabolism. It has also been shown to reduce the aggressiveness of the immune system and to improve eye health.

Supporting studies.

Calcium

calcium carbonate

Source: Biological

learn more

Calcium is an important component of many bodily functions. Certain genotypes require higher amounts of calcium for optimal bone health and to aid in detoxification.

Supporting studies.

Iron

iron bisglycinate

Source: Mineral

learn more

Iron is an important component of blood as it allows hemoglobin to carry oxygen. Some genetic variants can cause the excessive absorption of iron, which can damage organs.

Supporting studies.

Magnesium

magnesium hydroxide

Source: Mineral

learn more

Magnesium is an essential component of more than 300 enzymes, and therefore particularly important for metabolism, the functioning of the muscle cells, and also bone health.

Supporting studies.

Zinc

zinc bisglycinate

Source: Mineral

learn more

Zinc is needed by the body to correctly metabolize macronutrients, properly construct proteins and enzymes, to maintain normal bone, and to create new DNA.

Supporting studies.

Phytosterols

sito-, campe-, signma-

Source: Biological (pine)

learn more

In genotypes where omega 3 fatty acids have a negative impact on HDL cholesterol levels, phytosterols are a good alternative to help improve cholesterol levels.

Supporting studies.

Copper

copper sulphate

Source: Mineral

learn more

Copper is an important component of many enzymes and is therefore an important trace element for metabolism. It has also been shown to reduce the aggressiveness of the immune system and to improve eye health.

Supporting studies.

Calcium

calcium carbonate

Source: Biological

learn more

Calcium is an important component of many bodily functions. Certain genotypes require higher amounts of calcium for optimal bone health and to aid in detoxification.

Supporting studies.

Iron

iron bisglycinate

Source: Mineral

learn more

Iron is an important component of blood as it allows hemoglobin to carry oxygen. Some genetic variants can cause the excessive absorption of iron, which can damage organs.

Supporting studies.

Our Method

A U-shaped curve describes when too much - or too little - of something has a negative impact. In essence, it describes a nutrient "sweet spot" - which is different for every person. We identify your ideal range and dose for each nutrient and deliver it in a bespoke daily formula.

The science of nutrigenetics and metabolomics power our method. Nutrigenetics is the science of how slight genetic variations, inherited from your parents, impact how your body absorbs and metabolizes nutrients. Metabolomics infers nutrient function by assessing levels of metabolites (i.e. byproducts), produced through nutrient utilization.

Our Method

A U-shaped curve describes when too much - or too little - of something has a negative impact. In essence, it describes a nutrient "sweet spot" - which is different for every person. We identify your ideal range and dose for each nutrient and deliver it in a bespoke daily formula.

The science of nutrigenetics and metabolomics power our method. Nutrigenetics is the science of how slight genetic variations, inherited from your parents, impact how your body absorbs and metabolizes nutrients. Metabolomics infers nutrient function by assessing levels of metabolites (i.e. byproducts), produced through nutrient utilization.

Tests & Data

Our DNA Test analyzes 50+ SNPs (single nucleotide polymorpisms) that are proven to impact nutrient needs due to the influence on nutrient absorption, distribution, metabolism, excretion, and receptor function. All gene variants adhere to our medical-grade bar of proof to impact nutrient needs: 3 different studies by 3 different researchers in 3 different test populations (3x3x3 min.).

Our Blood Nutrient Test leverages metabolite analysis (80+ metabolites) to show how nutrients function in the body. This analysis reveals functional nutrient deficiencies that are missed in traditional blood testing. There are only a handful of labs in the world that can perform this test.

Tests are analyzed in our licensed medical-genetics laboratory certified ISO 9001, 15189, and 22000 - boasting 100% genetic testing accuracy over 10 years, determined by an external proficiency program. Your data is 100% private and secure.

Tests & Data

Our DNA Test analyzes 50+ SNPs (single nucleotide polymorpisms) that are proven to impact nutrient needs due to the influence on nutrient absorption, distribution, metabolism, excretion, and receptor function. All gene variants adhere to our medical-grade bar of proof to impact nutrient needs: 3 different studies by 3 different researchers in 3 different test populations (3x3x3 min.).

Our Blood Nutrient Test leverages metabolite analysis (80+ metabolites) to show how nutrients function in the body. This analysis reveals functional nutrient deficiencies that are missed in traditional blood testing. There are only a handful of labs in the world that can perform this test.

Tests are analyzed in our licensed medical-genetics laboratory certified ISO 9001, 15189, and 22000 - boasting 100% genetic testing accuracy over 10 years, determined by an external proficiency program. Your data is 100% private and secure.

AI Precision Dosing
100% Data Security
400+ Peer Reviewed Studies

The Pinnacle Of Personalized Nutrition

determine your precise nutrient needs at home

analyze 50+ genes and 80+ blood metabolites

accurate dosing of 18 research-backed ingredients

licensed medical genetics lab with 100% data security

slow-release microbeads provide optimal absorption

precision dosing of each nutrient to the mcg or mg

nutrigenetic method backed by 400+ PR studies

10+ years of technology backing precision formulas

100% testing accuracy, 200k+ analyses per month

in-house and 3rd party testing + state-of-the-art QC

algorithm auto-adjusts nutrient formula over time

Dr. Wallerstorfer
Founder, CTO, PhD, BSc
Dr. Diaz
PharmD, FAARM, FMNM, ABAAHP, RPh, METS
Rachel Sanders
Founder, CEO, Harvard MBA
Dr. Harris
MD, PharmD, MBA
Jordan Mazur
MS, RD, NFL
Tye Jensen
BS, Founding Team

Pinnacle Of Personalized Nutrition

50+ genes and 80+ metabolites

18 research-backed ingredients

licensed medical genetics lab

slow-release microbeads

precision doses of each nutrient

backed by 400+ PR studies

10+ years of pioneering tech

100% genetic testing accuracy

in-house and 3rd party testing

algorithm auto-adjusts over time

Dr. Wallerstorfer
Founder, CTO, PhD, BSc
Dr. Diaz
PharmD, FAARM, FMNM, ABAAHP, RPh, METS
Rachel Sanders
Founder, CEO, Harvard MBA
Dr. Harris
MD, PharmD, MBA
Jordan Mazur
MS, RD, NFL
Tye Jensen
BS, Founding Team

Need More Info?

Chat with us! Use the orange chat bubble in the bottom right to speak to a founding member of our team.

A platform to learn about your body and leverage crucial biometric data to achieve optimal health.

Now, we all have access to affordable medical-grade testing and data-driven solutions to determine our unique biological needs and elegantly meet them. Through technology, Rootine ties biometric testing and nutritional solutions together.

Understanding DNA and Nutrition

Common variations in your genetic code impact how you absorb, distribute, metabolize, and excrete key vitamins, minerals, and other nutritional substances. These slight variations are called single nucleotide polymorphisms (abbreviated “SNPs”) and alter the way the gene product is built. Slight variations in the corresponding enzymes and receptors adversely impact their function. The Rootine DNA Test analyzes 50+ gene variants that are research proven to impact nutrient needs.

- 11% of people have a SNP in their VDR gene, which creates the Vitamin D Receptor. This variation results in a less efficient binding between vitamin D and the receptor. Carriers need ~2x more vitamin D.

- 85% of people have SNPs in their MTHFR gene, which creates the enzyme that activates folate. These variations reduce the efficiency of this enzyme. Carriers often need pre-activated folate (methylfolate).

- 0.5% of people have SNPs in their HFE gene which alters the way the body regulates iron absorption. Carriers absorb far too much iron which becomes poisonous to their body. All iron is removed from their formula.

We’re proud to exclusively analyze and provide nutrient recommendations based on gene variants that are supported by medical-grade bar-of-proof to influence nutrient needs. This way you know your formula is built on verified science, not conjecture.

- Dr. Daniel Wallerstorfer PhD, Bsc, Founder of Rootine

Understanding Blood Testing and Metabolites

Blood testing is one of the most effective ways to determine which nutrients you need and helps monitor the success of a supplement program or dietary change over time. The science of metabolomics allows Rootine to go a step beyond traditional blood testing. With this technology, we can determine how nutrients are working in your body - which is considerably more useful information than just how much of a nutrient is in your blood.

Metabolite analysis considers molecules that are generated as byproducts of nutrient utilization (absorption, metabolism, excretion, etc.). When the levels of these byproducts are too high - or too low - we learn that a given nutrient is not performing its function properly in the body.

In addition, metabolite analysis provides deep insights into other aspects of metabolism, like how your body is metabolizing carbohydrates, if your diet is providing sufficient protein, if your body is using protein too rapidly, how well your body can detoxify heavy metals, how healthy your mitochondria are, if you are prone to kidney stones, and more.

We’ve been using similar technology in the medical field for years but at a price point 5x higher than what is offered at Rootine. It’s a significant improvement beyond traditional blood testing and drills down into metabolism, revealing weaknesses.

- Dr. Javier Diaz PharmD, FAARM, FMNM, ABAAHP, RPh, METS

Supplemental Nutrients and Microbeads

Every person has a sweet spot for their optimal daily intake of vital nutrients. The level for each nutrient is determined by a variety of factors, including genetics, current nutrient status, age, weight, health status, diet, lifestyle and more. To add complexity, these ideal intakes can change over time due to increasing age, health changes, and fluctuations in nutrient levels.

In short, determining optimal nutritional intakes is an incredibly complex equation unique to every person. The current standard system of RDAs (recommended daily allowances) and DVs (daily values) for nutrient intakes lacks these critical nuances that directly determine each person’s unique needs. These systems are a well-intentioned approach to provide a succinct reference to the level of nutrients most people need; however, optimal outcomes are built on precision, personalized nutrition - not population-level generalizations. Rootine is built to fill this gap.

The elegance of Rootine's approach is two-fold: 1) by analyzing DNA data, blood status, and relevant lifestyle factors (age, weight, habits, dietary preferences, etc.), we are able to create the most complete and accurate understanding of an individual's true requirements, and 2) our innovative microbead delivery system provides precision dosing of each nutrient to the micogram or milligram - coupled with enhanced delivery from the slow-release and spatial nutrient separation. Microbeads are the leading oral nutrient delivery system.

We saw a hole in the personalized health industry. Comprehensive testing solutions were lacking and no brand had the capability of offering bespoke formulas with precise doses. We created Rootine to fill this gap.

- Rachel Sanders MBA, Founder of Rootine

Need More Info?

Chat with us! Use the orange chat bubble in the bottom right to speak to a founding member of our team.